WINTER 2008

Perspectives

Letters

Cancer Controversy in Cardiology: Does Ezetimibe Raise Cancer Risk?

Genomic Medicine: Breaking the Code

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Brain Tumors

Temozolomide Fails to Best PCV in High-Grade Gliomas

Whole Brain Irradiation Risks Cognitive Problems

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Breast Cancer

Molecular Breast Imaging Sees Tumors in Dense Breasts

MBI Needs Dose Reduction to Be Alternative to Mammography

New Cardiac Guidelines for Trastuzumab

Troponin, BNP Testing Advocated for Detecting Cardiotoxicity

Trastuzumab-Tied Heart Damage More Common in Clinic

Accelerated Whole-Breast Irradiation as Good as Standard Dose

HER2 Conversion During Treatment May Explain Trastuzumab Resistance

Insurer to Pay for Extra HER2 Tests

Adjuvant Chemo Overcomes Poor BRCA1 and BRCA2 Prognoses

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Gastrointestinal Malignancies

Vioxx Fails to Aid Survival, But Some Patients Benefit

DNA-Based Colon Cancer Screen Has 80% Sensitivity

Endoscopic Injection of Biologic Tames Esophageal Tumors

Heat Shock Protein 90 Inhibitor: 1st Phase III Trial Targets GIST

EndoTAG-1 Plus Gemcitabine Ups Survival in Pancreatic Cancer

Preoperative Staging by CT Favored in Pancreatic Cancer

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Genitourinary Malignancies

Adding Radiotherapy to Hormones Boosts Survival

Web Tool Focuses Prostate Cancer Treatment Decisions

Mortality Higher in Older Men With NHT, Brachytherapy

8-Month NHT Improves Freedom From Failure, but Not Survival

Provenge Vaccine Fails to Meet Interim Study End Point

Sorafenib Benefit Shown in Elderly Patients With Advanced RCC

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Gynecologic Malignancies

Trabectedin Delays Progression of Recurrent Ovarian Cancer

Intense Radiotherapy Fails to Aid Survival in Cervical Cancer

Sexual Dysfunction After Gyn. Cancer Care

1 in 10 Survivors Reports 'Unexpected Defecation'

Commentary: Life After Treatment of Gynecologic Malignancies

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Head and Neck Cancers

Phase II Study Finds Chemoradiation Plus Cetuximab Safe

EXTREME: Cetuximab Plus Chemo Raises Progression-Free Survival

Cetuximab + Radiation Survival Gain Is Durable at 5 Years

Weekend Breaks Don't Cut Efficacy of Accelerated Radiotherapy

Standard Chemoradiation Tops Accelerated Regimen

Low -Tubulin II: Longer Survival in Advanced HNSCC

P16 Positivity Means Better Oropharyngeal Cancer Survival

FAQs on HPV in Head and Neck Cancers Answered

Viral DNA Level Predicts Nasopharyngeal Carcinoma Outcome

New Drug Class Making Waves in Advanced Thyroid Cancer

Should Endocrinologists Prescribe Tyrosine Kinase Inhibitors?

Novel Strategy Reduces Radioiodine Use in Thyroid Cancer

Amifostine Does Not Affect Survival in Head and Neck Cancer

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Hematologic Malignancies

Biologic Prognostic CLL Markers Have Limited Use So Far

Rare Case of Relapsing Leukemia Cutis Appears Only in Skin

Nonablative Allogeneic Transplants Tame Some Lymphomas

New & Approved: Ontak Solution for IV Injection

Subcutaneous Panniculitic T-Cell Lymphoma Has Two Types

Exceptions Seen in Histology of Rare Aggressive Lymphoma

New & Approved: Treanda for Injection

Outpatient Transplant in Multiple Myeloma: Two Views

Gene Variants Can Predict Mortality in Multiple Myeloma

Don't Rely Only on Scoring Systems When Deciding Care for Myelodysplasia

Common Errors in Treatment of Myelodysplasia

Trials of JAK2 Inhibitors Offer Hope for Myeloproliferative Disorders

JAK2 Testing Influences Prognosis of Myeloproliferative Disorders

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Lung Cancer

AVAIL: Bevacizumab Fails in Final Survival Analysis

EGFR Screening Extends Survival With Erlotinib Use

First-Line Gefitinib Benefits Asian Patients With NSCLC

PCR Test Can Tell Squamous From Nonsquamous NSCLC

New & Approved: Alimta

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Melanoma

Temozolomide Fails to Improve Survival in EORTC Trial

After EORTC 18032: Is Melanoma Research at an Impasse?

Delayed Response Seen With New Anti-CTLA-4 Agents

Melanoma Risk Increases With TNF Blockers in Cancer Survivors

False-Negative Sentinel Biopsy Rate Higher in Head, Neck

Thin Melanoma Regression Insufficient to Order SLN Biopsy

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Patient Care

Cancer Outcomes Improved With Palliative Care Nursing

Single Dose of Radiotherapy Eases Spinal Compression

Intravenous Iron Boosts Erythropoiesis During Chemotherapy

Joint Stiffness Is Common With Aromatase Inhibitor Therapy

New & Approved: Sancuso Transdermal System

Palifermin Reduces Oral Mucositis but Skeptics Question Safety

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Practice Trends

Physician Fee Rule Includes 1.1% Raise, Plus Bonuses

ICD-10 Transition Likely to Carry Big Price Tag for Physicians

Medicare Offers Bonus to Push E-Prescribing Beginning in 2009

E-Prescribing: Qualifying for the Medicare Bonus

Black Box Warning on ESAs May Justify Higher Billings

Add Revenue Sources to Cope, Community Oncologists Urged

Managing Cash Flow in a Community Oncology Group

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